NASC Stock Detail Page
NASC ID: N9857
Name: jag-1
ABRC stock number: CS9857
Description: pSKI015 insertion. Arabidopsis Knockout Facility at the University of Wisconsin-Madison
Donation Date: 2008-06-02
Donated by: | Max-Planck-Institute for Developmental Biology Detlef Weigel |
Donor Number: jag-1
Part of : Homozygous lines
Stock type: individual line
Material type: seed
Comment: related stock in background Ws-2: N9505
Status | Price (£) |
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Available | £11.00 |
Germplasm Info
Mutagen: T-DNA Insertion
Background: Col-0
Segregation status: homozygous
Associated Polymorphisms
When available, select a locus to display it at the AIP or view the EMBL record at the EBI.
Gene: | Allele: | Locus: | AGI code: |
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Phenotype
Loss of JAGGED function causes organs to have serrated margins. In leaves, the blade region is most severely affected. In sepals, petals and stamens, the strongest defects are seen in the distal regions. By monitoring cell-cycle activity in developing petals with the expression of HISTONE 4, we show that JAGGED suppresses the premature differentiation of tissues, which is necessary for the formation of the distal region. The localization of defects overlaps with the expression domain of JAGGED, which is restricted to the growing regions of lateral organs.
References
Dinneny, J.R. et al. 2004. The role of JAGGED in shaping lateral organs. Development 131(5):1101-10.PubMed ID: 14973282.
Dinneny, J.R., Weigel, D. & Yanofsky, M.F. 2006. NUBBIN and JAGGED define stamen and carpel shape in Arabidopsis. Development 133(9):1645-55.PubMed ID: 16554365.